You’re not diabetic. You’re not alcoholic. You don’t have kidney disease. You take B vitamins but you still have neuropathy. Unfortunately, about 30% of patients with neuropathy are diagnosed as idiopathic (we don’t know why.) The scientific literature may have an answer for some of those in the idiopathic group. It seems gluten sensitivity is associated with neuropathy. There is a simple blood test for anti gliadin antibodies (gliadin is a form of gluten) and a test for the HLA-DQ gene which will help determine if you are gluten sensitive. Let’s look at some scientific literature.
Celiac disease presenting with motor neuropathy: effect of gluten free-diet.
Rigamonti A, Magi S, Venturini E,Morandi L, Ciano C, Lauria G.
Neuromuscular Diseases Unit, National Neurological Institute Carlo Besta, Via Celoria 11, 20133 Milan, Italy.
Celiac disease is a rare cause of neuropathy that most commonly presents with symmetric distal sensory disturbances. We describe two patients with celiac disease in whom neuropathy presented unusually with progressive weakness of the limbs. In both patients a gluten-free diet induced a significant improvement of muscle strength and neurophysiological abnormalities, suggesting a direct pathogenetic role of sensitivity to gluten. Celiac disease should be considered in patients with idiopathic neuropathy even when gastrointestinal symptoms are absent.
Many of us who treat neuropathy patients are aware of this aspect but I see patients everyday who have been worked up for neuropathy but are unaware of this possibility.
Dr. Nelson Mane Talks About Two Common Medications That May be Causing Your Peripheral Neuropathy
Many patients diagnosed with idiopathic (we don’t know why) peripheral neuropathy may have neuropathy induced by medication and are unaware of it. The most common cause of neuropathy in the U.S is diabetes
The most common cause in the world is Leprosy. Other common causes in the U.S include things such as alcoholism, B vitamin deficiency, HIV medication, kidney disease and chemotherapy. High cholesterol is seen in the U.S and is most times treated with statin drugs. A thorough investigation into causes of neuropathy should include statin medications especially when more common causes can not be established. pharmacotherapy, 2004 Sep;24(9):1194-203.
Statin-associated peripheral neuropathy: review of the literature.
ChongPH, Boskovich A, Stevkovic N. Bartt RE.
Department of Pharmacy, John H. Stroger, Jr Hospital, School of Pharmacy, University of Illinois at Chicago, IL 60612-3715, USA.
Various pharmacologic agents are available for the treatment of hypercholesterolemia, including 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, commonly referred to as statins, which offer favorable lipid-lowering effects and reductions in morbidity and mortality. Statins are usually better tolerated than other lipid-lowering agents and therefore have become a mainstay of treatment for hypercholesterolemia. However, recent case reports of peripheral neuropathy in patients treated with statins may have gone unnoticed by health care professionals. To evaluate the possible link between statins and peripheral neuropathy, literature searches using MEDLINE (January 1993--November 2003) and International Pharmaceutical Abstracts (January 1970--June 2002) were performed. Key search terms were statin, neuropathy, and HMG-CoA reductase inhibitors. Based on epidemiologic studies as well as case reports, a risk of peripheral neuropathy associated with statin use may exist; however, the risk appears to be minimal. On the other hand, the benefits of statins are firmly established. These findings should alert prescribers to a potential risk of peripheral neuropathy in patients receiving any of the statins; that is, statins should be considered the cause of peripheral neuropathy when other etiologies have been excluded.
PMID: 15460180 [PubMed - indexed for MEDLINE]
Another commonly prescribed antibiotic is the Flouroquinolones (ie Cipro). Dr. Nelson Mañé is a board certified chiropractic orthopedist and neurologist in Tampa who is one of the leading doctors in the use of HPLT for peripheral neuropathy. The treatment can be used even if standard treatments with Neurontin, Lyrica, Cymbalta and Anodyne have failed. His office has performed over 5000 HPLT treatments for neuropathy patients.
For more information about the treatment of Peripheral Neuropathy with High Power Laser Therapy or about Dr. Nelson Mane D.C. please visit our website at http://www.manecenter.com/neuropathy.htm.
Celiac disease presenting with motor neuropathy: effect of gluten free-diet.
Rigamonti A, Magi S, Venturini E,Morandi L, Ciano C, Lauria G.
Neuromuscular Diseases Unit, National Neurological Institute Carlo Besta, Via Celoria 11, 20133 Milan, Italy.
Celiac disease is a rare cause of neuropathy that most commonly presents with symmetric distal sensory disturbances. We describe two patients with celiac disease in whom neuropathy presented unusually with progressive weakness of the limbs. In both patients a gluten-free diet induced a significant improvement of muscle strength and neurophysiological abnormalities, suggesting a direct pathogenetic role of sensitivity to gluten. Celiac disease should be considered in patients with idiopathic neuropathy even when gastrointestinal symptoms are absent.
Many of us who treat neuropathy patients are aware of this aspect but I see patients everyday who have been worked up for neuropathy but are unaware of this possibility.
Dr. Nelson Mane Talks About Two Common Medications That May be Causing Your Peripheral Neuropathy
Many patients diagnosed with idiopathic (we don’t know why) peripheral neuropathy may have neuropathy induced by medication and are unaware of it. The most common cause of neuropathy in the U.S is diabetes
The most common cause in the world is Leprosy. Other common causes in the U.S include things such as alcoholism, B vitamin deficiency, HIV medication, kidney disease and chemotherapy. High cholesterol is seen in the U.S and is most times treated with statin drugs. A thorough investigation into causes of neuropathy should include statin medications especially when more common causes can not be established. pharmacotherapy, 2004 Sep;24(9):1194-203.
Statin-associated peripheral neuropathy: review of the literature.
ChongPH, Boskovich A, Stevkovic N. Bartt RE.
Department of Pharmacy, John H. Stroger, Jr Hospital, School of Pharmacy, University of Illinois at Chicago, IL 60612-3715, USA.
Various pharmacologic agents are available for the treatment of hypercholesterolemia, including 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, commonly referred to as statins, which offer favorable lipid-lowering effects and reductions in morbidity and mortality. Statins are usually better tolerated than other lipid-lowering agents and therefore have become a mainstay of treatment for hypercholesterolemia. However, recent case reports of peripheral neuropathy in patients treated with statins may have gone unnoticed by health care professionals. To evaluate the possible link between statins and peripheral neuropathy, literature searches using MEDLINE (January 1993--November 2003) and International Pharmaceutical Abstracts (January 1970--June 2002) were performed. Key search terms were statin, neuropathy, and HMG-CoA reductase inhibitors. Based on epidemiologic studies as well as case reports, a risk of peripheral neuropathy associated with statin use may exist; however, the risk appears to be minimal. On the other hand, the benefits of statins are firmly established. These findings should alert prescribers to a potential risk of peripheral neuropathy in patients receiving any of the statins; that is, statins should be considered the cause of peripheral neuropathy when other etiologies have been excluded.
PMID: 15460180 [PubMed - indexed for MEDLINE]
Another commonly prescribed antibiotic is the Flouroquinolones (ie Cipro). Dr. Nelson Mañé is a board certified chiropractic orthopedist and neurologist in Tampa who is one of the leading doctors in the use of HPLT for peripheral neuropathy. The treatment can be used even if standard treatments with Neurontin, Lyrica, Cymbalta and Anodyne have failed. His office has performed over 5000 HPLT treatments for neuropathy patients.
For more information about the treatment of Peripheral Neuropathy with High Power Laser Therapy or about Dr. Nelson Mane D.C. please visit our website at http://www.manecenter.com/neuropathy.htm.
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