Monday, February 8, 2010

Facts and Alternatives Regarding Treatments for Prostate Cancer


Patients who suffer from prostate cancer have many alternatives to treat their affection but they should know all the opinions and investigate therapies before they choose the treatment that suits them. First of all, a person who suffer from prostate cancer should ask for a second opinion, inform himself from books or internet about his condition and also take along detailed list of questions and record the answers. Moreover, the patient shoud be aware of the doctor's experience in treating prostate cancer and also that the doctors in charge should treat the whole patient, not just the prostate and not in the last place the family or a friend support may help a lot.

Furthermore, choosing a treatment for prostate cancer can be a hard task for the patient and for the doctors as well. The treatments are divided in certain groups and each procedure is performed by a specialist. For instance, radiation oncologists in radiation, urologists usually specialize in surgery and cryoablation, both internal and external and usually used alone or in combination. Each type of treatment seem to bring successfully results, including no immediate treatment other than careful observation for elder men.

On the other hand, these types of treatments like surgery, cryoablation and radiation can have side effects, such as impotence and incontinence. Moreover, other side effects are loss of the sex drive, weight gain and also by performing hormonal therapy, the amount of testosterone in the bloodstream is reduced and thereby deprives a prostate tumor of a necessary stimulus, used to extend life and delay the disease to progress.

Moreover, many clinical trials are testing new treatments for prostate cancer and patients can choose the right treatment depending on the type of cancer that they have. So, some of the experimental treatments which seem to be quite effective are: chemotherapy which uses new drugs in order to help men with advanced prostate cancer, immunotherapy which helps the body to fight against cancer and also neoadjuvant hormonal therapy that has the role in reducing the prostate tumor in order to increase success rates of surgery or radiation.

All in all, people who suffer from prostate should weight carefully the options and choose the right procedure in a short time. Moreover, immunotherapies may help men with late-stage cancer and also some of these therapies can be used to prevent recurrence of cancer following surgery or radiation.

New Solutions in Fighting Advanced Prostate Cancer
Scientists have been trying to find a cure for advanced prostate cancer or at least a solution for delaying the disease’s effects. So, they have created a vaccine that seems to improve the immune response to fight prostate cancer. The vaccine is still under clinical trials to test its complete efficiency, to adjust doses and to see if it works on less advanced prostate cancer.

Eric J. Small, MD, UCSF professor of medicine and urology, along with other 19 US institutions conducted the study which was funded by the Dendreon Corporation (the developer of the vaccine) based in Seattle, Washington. They tested 31 patients who were suffering of asymptomatic metastatic hormone refractory prostate cancer (HRPC) and had only one year left to live. The study was designed for observing if the disease progression will be delayed and patients will survive longer. In July1, 2006 the Journal of Clinical Oncology published the first conclusions of this research.

After two months of treatment with Provenge, 20 of the patients developed a responsive immunity against a protein situated on the surface of prostate cells (prostatic acid phosphatase). In these patients, the disease progressed after 34 weeks, but in the case of the other 11 patients the disease progressed after 13 weeks.

The vaccine was well tolerated by patients and the side effects were mild: fever and chills. Five of the subjects declared they had mild urinary problems. This is good news because chemotherapy gives a lot of unbearable side effects.

The vaccine has been made out of a genetically engineered protein and a dendritic cell provided from the patient’s bloodstream.

T.J. Koerner, PhD, scientific program director for the American Cancer Society (ACS)said that the vaccine needs to be still under trials because doses need to be adjusted and drug combination must be tried. Also, the scientists want to see if this vaccine will work on less advanced prostate cancer. Most of the patients can follow a treatment based on surgery, radiation and hormone therapy, but asymptomatic metastatic HRPC is known to be resistant to hormone therapy and every year more than 30,000 men die because and no other treatment is effective against the disease, this is why a treatment is urgently required.


Thursday, February 4, 2010

Prostate Cancer Information


The purpose of this article is to describe very briefly the prostate gland; its functions and potential diseases associated with it. General Prostate Cancer Information - about half the population has a prostate gland but how many people actually know what it is? The prostate is found in all males in the mammal category of the animal world, including humans. The prostates function in life is to produce, store and secrete a clear fluid during moments of orgasm. This fluid helps carry the sperm out of the body and makes up about one third of the volume expelled during ejaculation. The prostate is located at the outlet of the bladder and surrounds the urethra (tube your urines passes through); it also sits against the outer wall of the rectum.

Disorders associated with the prostate

Amyloid
Normally affecting men who are more senior in age, Amyloid (known as Corpora amylacea) is a dense collection of calcified protein based matter that collects in the prostates ducts making it difficult for the prostate to release fluid. This condition can also mean there are other underlying issues in the prostate region.

Prostatitis
Prostatitis is a build up of inflammation in the prostate, over time the inflammation can make the prostate swell in size causing the tubes carrying urine to become blocked making it difficult and painful to urinate, if urination is possible at all.

Benign prostatic hyperplasia
Similar to Prostatis, Benign prostatic hyperplasia is the name given to a condition where the prostate becomes enlarged, this is not caused by inflammation but can be a natural occurrence over time and mainly affects the older male population.

This condition can block the urinary tubes or stop urination being possible all together.

Prostate cancer
For you to possess prostate cancer information is critical to you if you are male and over 50. Prostate cancer is the most dangerous of all prostate problems and is the most common cancer affecting older men. Prostate cancer is also a condition that can kill quite easily; this is because the cancerous cells flourish and multiple out of control, moving into other part of the body like the bones and nearby internal tissue.

The most common symptoms associated with prostate cancer are that it can cause pain in the lower abdominal region during urination, difficulty urinating and cause a lack of ability to gain an erection. There are many other symptoms involved with prostate cancer, but they are more subtle.

Summary
It is commonly suggested that men who are more senior in age should have regular rectal exams from their doctor so the prostate can be checked. As mentioned earlier, the prostate sits against the outer wall of the rectum. For those who are younger in age it is important that they are educated about the affects the prostate has on the body.

Finding Prostate Cancer Treatment Options
With prostate cancer estimated to affect as many as 1 in 6 men, any new research developments that may affect treatment are extremely noteworthy. Because the risks of having prostate cancer increase dramatically with age, every generation is in a race against the clock to find the most effective treatment methods, or prevention methods, possible.

Recently a medical study on men with prostate cancer introduced very interesting news that contradicted some previously held beliefs in the medical community. Some physicians have withheld potentially curative treatment in older men because of a concern about side effects of radiation or surgery. Other physicians have used hormone therapy as a means of delaying cancer progression instead of offering potentially curative treatment.

This new study by Robert Wood Johnson Medical School, however, suggests that drug treatment alone does not improve survival rates of men taking it, and might actually be hindering their improvement. The study was published in the Journal of the American Medical Association in July.

The prostate cancer information generated by this article studied about 20,000 men, including Medicare patients, whose prostate cancer had not spread to other areas of the body. The study took 6 years to complete, as information was gathered and the men were studied. All study participants were over the age of 66, which means that the data drawn from the study is particularly relevant to older men, but not necessarily accurate for younger men. Average age of a study participant was 77.

Researchers found that the typical treatment of testosterone-blocking drugs might have more drawbacks than benefits. The testosterone-blockers are meant to keep cancer cells from growing, but also have side effects such as bone loss, impotence, and increased risk for diabetes and heart disease. Ultimately, a treatment plan of the testosterone-blocking drugs alone, in older men, didn't appear to be effective.

For men considering Georgia prostate cancer surgery, this study does not influence the need for curative surgery or radiation. Often the antihormone drugs can be very effective when they are paired with surgery or radiation. To maximize the effectiveness of a cancer treatment plan for Georgia men, prostate cancer might require surgery or radiation, rather than drug treatment alone.

Researchers theorized that many men felt they were improving their health by taking the drugs without surgery or radiation, because it was a better course of action than doing nothing. For older men looking for information about Georgia prostate cancer treatment, the study offers an important topic to bring up with their doctors. For Georgia men, prostate cancer treatment might require surgery, rather than the simpler approach of a drug treatment.

With the continued research and studies being done, advances in Georgia prostate cancer treatment are continually being made. At this point in time, however, drug treatment alone doesn't seem to be an effective method in the fight against prostate cancer.