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First Signs of Breast Cancer Progression

Tuesday, September 1, 2009 6:44:00 AM Posted by Cancer Centers

In the U.S., over 90 percent of breast cancer diagnoses happen during the early breast cancer stages. Early detection is good news for the patient as it often translates to effective treatment.

Other disease characteristics, like hormone receptors and lymph nodes, can aid in prognosing results and help doctors and patients choose the right treatment.

Although breast cancer is on the rise in North America and the UK, the mortality rate is decreasing. This decline in mortality is credited to an increased number of women obtaining mammograms, improved evaluation techniques, and effective ancillary treatments.

Thus if the majority of diagnosed breast cancer cases are discovered during the preliminary stages, what effect does that have on patients and what are the best treatment courses?

The Early Stages of Breast Cancer
Earlier breast cancer stages are called TNM stages 1, 2 and 3a. This scoring system approximates how far the carcinoma has advanced. Most instances of early-stage breast cancer are curable through surgery, radiation therapy or systemic therapy. The survival rate for patients diagnosed this early have a 5-year success rate of over 75%.

Normal Treatment Reactions
Treatment reaction generally hinges on lymph node engagement, the size and grade of any tumors, the age of the patient, hormone (estrogen and progesterone) receptors, and the status or condition of biologic markers like HER2/neu.

Lymph Node Indicators
Lymph nodes are an effective way to predict the effects of breast cancer. Essentially, the more positive lymph nodes that are present, the lower the patient's survival rate and the higher the chances of relapse. Commonly, patients with earlier stage breast cancer are classified into those presenting negative nodes, 1 to 3 positive lymph nodes, 4 to 9 positive nodes, or 10 and more nodes.

Tumor Size
If a patient exhibits negative lymph nodes and a tumor that is smaller than 1cm, the prognosis is often very good. Most doctors use tumor size as an effective and critical indicator during the early stages of this disease.

The Grade of Tumor
As the grade of the tumor increases, so does the potential relapse rate?

Estrogen and Progesterone Receptors
Estrogen and progesterone receptors within the tumor are also used to prognosticate breast cancer during the earlier stages. Generally, those patients with a receptor-positive form of breast cancer tend to have a better prognosis and survival rate than those who don't.

HER2/neu as an Indicator
HER2/neu is what's called a marker - it's a biological element typically present in the body or within the tumor in about 25% of all breast cancer cases. When HER2/neu levels are high, that usually translates to a more aggressive variety of breast cancer and a worse prognosis.

Age of the Patient
Generally, patients who are older (50 and up) have a better prognosis than patients under the age of 35.

Breast Cancer Facts
The breast cancer signs and symptoms can be widely different for every woman. Some experience lumps, some experience skin changes that appear quite drastic and other women get no definite signs of breast cancer.

Some women experience similar signs and symptoms of breast cancer when it may just be a simple infection or maybe a cyst. All women of all ages – from teens upwards – should check their breasts for unusual lumps and bumps. If you think you find a lump or your breasts feel and look different, it is best to get an appointment with a doctor as soon as possible.

The prognosis of a diagnosis for breast cancer can sometimes take many weeks and can include many different types of testing to undergo. This can be extremely frustrating and quite an upsetting time in any woman’s life. You can sit down with your doctors and formulate some kind of plan for treatment which will be specifically tailored just for you.

There are a few myths surrounding breast cancer and the breast cancer facts.

Some people believe that breast cancer only becomes a risk when you are older.

Some people also believe that if breast cancer doesn’t run in the family they won’t actually get breast cancer. It is thought that nearly 80 percent of women who have had breast cancer have no family history of the disease.

It was reported years ago that antiperspirants can put women at risk of developing breast cancer. This is unfounded and has never been proved that a link between using antiperspirants and breast cancer even exists. It has also been reported that using birth control pills can contribute to a woman’s risk of developing breast cancer. There are many studies done over time that show no founded link between the two. One of the studies combined all the information received from all of the other studies and found a very slight increase. This increase was over time, but was not significant enough actually prove the link.

There has also been a lot of press about the association of high fat foods and the risk of breast cancer. While eating high fat foods isn’t good for health, there is no definitive research that the link between eating fatty foods and breast cancer actually exists. This could be a misinterpretation of the link between obesity and breast cancer which does actually exist and has been proven many times. If you make a lifestyle choice and eat lots of high fat foods, you will eventually become overweight and possibly obese. This will then in turn, increase your risk of developing breast cancer at a later date.


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